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1

Trans-Oval-Window Implants, A New Approach for Drug Delivery to the Inner Ear

Sircoglou, Julie, Gehrke, Maria, Tardivel, Meryem, Siepmann, Florence, Siepmann, Juergen, Vincent, Christophe

Journal:

Otology & Neurotology

Year:

2015

Language:

english

File:

PDF, 12.95 MB

english, 2015

2

Effects of film coating thickness and drug layer uniformity on in vitro drug release from sustained-release coated pellets: A case study using terahertz pulsed imaging

Louise Ho, Yvonne Cuppok, Susanne Muschert, Keith C. Gordon, Michael Pepper, Yaochun Shen, Florence Siepmann, Juergen Siepmann, Philip F. Taday, Thomas Rades

Journal:

International Journal of Pharmaceutics

Year:

2009

Language:

english

File:

PDF, 1.29 MB

english, 2009

3

Modeling of diffusion controlled drug delivery

Juergen Siepmann, Florence Siepmann

Journal:

Journal of Controlled Release

Year:

2012

Language:

english

File:

PDF, 1.00 MB

english, 2012

4

Using milling to explore physical states: The amorphous and polymorphic forms of dexamethasone

Marques, Paulo Filho, Willart, Jean-Francois, Siepmann, Juergen, Siepmann, Florence, Descamps, Marc

Journal:

Crystal Growth & Design

Year:

2018

Language:

english

File:

PDF, 1.20 MB

english, 2018

5

Cast lipid implants for controlled drug delivery: Importance of the tempering conditions

Frauke Kreye, Florence Siepmann, Anna Zimmer, Jean-Francois Willart, Marc Descamps, Juergen Siepmann

Journal:

Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 634 KB

english, 2011

6

Local controlled drug delivery to the brain: Mathematical modeling of the underlying mass transport mechanisms

J. Siepmann, F. Siepmann, A.T. Florence

Journal:

International Journal of Pharmaceutics

Year:

2006

Language:

english

File:

PDF, 913 KB

english, 2006

7

Novel polymeric film coatings for colon targeting: How to adjust desired membrane properties

Youness Karrout, Christel Neut, Daniel Wils, Florence Siepmann, Laetitia Deremaux, Pierre Desreumaux, Jürgen Siepmann

Journal:

International Journal of Pharmaceutics

Year:

2009

Language:

english

File:

PDF, 796 KB

english, 2009

8

pH-Sensitive Polymer Blends Used as Coating Materials to Control Drug Release from Spherical Beads: Elucidation of the Underlying Mass Transport Mechanisms

Florence Lecomte, Juergen Siepmann, Mathias Walther, Ross J. MacRae, Roland Bodmeier

Journal:

Pharmaceutical Research

Year:

2005

Language:

english

File:

PDF, 694 KB

english, 2005

9

New Insight into the Role of Polyethylene Glycol Acting as Protein Release Modifier in Lipidic Implants

Sandra Herrmann, Silke Mohl, Florence Siepmann, Juergen Siepmann, Gerhard Winter

Journal:

Pharmaceutical Research

Year:

2007

Language:

english

File:

PDF, 514 KB

english, 2007

10

Polymer Blends Used for the Coating of Multiparticulates: Comparison of Aqueous and Organic Coating Techniques

Florence Lecomte, Juergen Siepmann, Mathias Walther, Ross J. MacRae, Roland Bodmeier

Journal:

Pharmaceutical Research

Year:

2004

Language:

english

File:

PDF, 180 KB

english, 2004

11

Novel polymeric film coatings for colon targeting: Drug release from coated pellets

Youness Karrout, Christel Neut, Daniel Wils, Florence Siepmann, Laëtitia Deremaux, Marie-Pierre Flament, Luc Dubreuil, Pierre Desreumaux, Juergen Siepmann

Journal:

European Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 832 KB

english, 2009

12

Mobility of model proteins in hydrogels composed of oppositely charged dextran microspheres studied by protein release and fluorescence recovery after photobleaching

Sophie R. Van Tomme, Bruno G. De Geest, Kevin Braeckmans, Stefaan C. De Smedt, Florence Siepmann, Juergen Siepmann, Cornelus F. van Nostrum, Wim E. Hennink

Journal:

Journal of Controlled Release

Year:

2005

Language:

english

File:

PDF, 309 KB

english, 2005

13

Sustained release of nanosized complexes of polyethylenimine and anti-TGF-β2 oligonucleotide improves the outcome of glaucoma surgery

Ana L. Gomes dos Santos, Amélie Bochot, Aoife Doyle, Nicolas Tsapis, Juergen Siepmann, Florence Siepmann, Jeannette Schmaler, Madeleine Besnard, Francine Behar-Cohen, Elias Fattal

Journal:

Journal of Controlled Release

Year:

2006

Language:

english

File:

PDF, 976 KB

english, 2006

14

Mechanisms controlling protein release from lipidic implants: Effects of PEG addition

Sandra Herrmann, Gerhard Winter, Silke Mohl, Florence Siepmann, Juergen Siepmann

Journal:

Journal of Controlled Release

Year:

2007

Language:

english

File:

PDF, 858 KB

english, 2007

15

How Autocatalysis Accelerates Drug Release from PLGA-Based Microparticles: A Quantitative Treatment

Siepmann, Juergen, Elkharraz, Khaled, Siepmann, Florence, Klose, Diana

Journal:

Biomacromolecules

Year:

2005

Language:

english

File:

PDF, 271 KB

english, 2005

16

Aqueous HPMCAS coatings: Effects of formulation and processing parameters on drug release and mass transport mechanisms

Florence Siepmann, Juergen Siepmann, Mathias Walther, Ross MacRae, Roland Bodmeier

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2006

Language:

english

File:

PDF, 488 KB

english, 2006

17

Cross-linking of chitosan and chitosan/poly(ethylene oxide) beads: A theoretical treatment

Leticia Martinez, Florence Agnely, Bernard Leclerc, Juergen Siepmann, Marine Cotte, Sandrine Geiger, Guy Couarraze

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2007

Language:

english

File:

PDF, 473 KB

english, 2007

18

Drug release mechanisms from ethylcellulose: PVA-PEG graft copolymer-coated pellets

Susanne Muschert, Florence Siepmann, Bruno Leclercq, Brian Carlin, Juergen Siepmann

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2009

Language:

english

File:

PDF, 465 KB

english, 2009

19

Colon targeting with bacteria-sensitive films adapted to the disease state

Youness Karrout, Christel Neut, Daniel Wils, Florence Siepmann, Laetitia Deremaux, Luc Dubreuil, Pierre Desreumaux, Juergen Siepmann

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2009

Language:

english

File:

PDF, 509 KB

english, 2009

20

Drug release from extruded solid lipid matrices: Theoretical predictions and independent experiments

Sinan Güres, Florence Siepmann, Juergen Siepmann, Peter Kleinebudde

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2012

Language:

english

File:

PDF, 1.39 MB

english, 2012

21

Enzymatically degraded Eurylon 6 HP-PG: ethylcellulose film coatings for colon targeting in inflammatory bowel disease patients

Youness Karrout, Christel Neut, Florence Siepmann, Daniel Wils, Pierre Ravaux, Laetitia Deremaux, Marie-Pierre Flament, Luc Dubreuil, Mohamed Lemdani, Pierre Desreumaux, Juergen Siepmann

Journal:

Journal of Pharmacy and Pharmacology

Year:

2010

Language:

english

File:

PDF, 417 KB

english, 2010

22

Development and evaluation of sustained-release clonidine-loaded PLGA microparticles

Amélie Gaignaux, Jonathan Réeff, Florence Siepmann, Juergen Siepmann, Carine De Vriese, Jonathan Goole, Karim Amighi

Journal:

International Journal of Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 709 KB

english, 2012

23

Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors

Flipo, Marion, Desroses, Matthieu, Lecat-Guillet, Nathalie, Villemagne, Baptiste, Blondiaux, Nicolas, Leroux, Florence, Piveteau, Catherine, Mathys, Vanessa, Flament, Marie-Pierre, Siepmann, Juergen,

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 3.98 MB

english, 2012

24

pH-Sensitive Polymer Blends used as Coating Materials to Control Drug Release from Spherical Beads: Importance of the Type of Core

Lecomte, Florence, Siepmann, Juergen, Walther, Mathias, MacRae, Ross J., Bodmeier, Roland

Journal:

Biomacromolecules

Year:

2005

Language:

english

File:

PDF, 203 KB

english, 2005

25

Lipid implants as drug delivery systems

Kreye, Frauke, Siepmann, Florence, Siepmann, Juergen

Journal:

Expert Opinion on Drug Delivery

Year:

2008

Language:

english

File:

PDF, 3.12 MB

english, 2008

26

Mo2011 In Vivo Efficacy of Microflora Sensitive Polysaccharide-Based Film Coatings for Colon Targeting: A Promising Tool for IBD Therapy

Karrout, Youness, Dubuquoy, Laurent, Neut, Christel, Siepmann, Florence, Wils, Daniel, Dubreuil, Luc, Desreumaux, Pierre, Siepmann, Juergen

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 80 KB

english, 2012

27

Carrageenan as an Efficient Drug Release Modifier for Ethylcellulose-Coated Pharmaceutical Dosage Forms

Siepmann, Florence, Muschert, Susanne, Zach, Stefanie, Leclercq, Bruno, Carlin, Brian, Siepmann, Juergen

Journal:

Biomacromolecules

Year:

2007

Language:

english

File:

PDF, 277 KB

english, 2007

28

Accelerated ketoprofen release from spray-dried polymeric particles: importance of phase transitions and excipient distribution

Gue, Emilie, Muschert, Susanne, Willart, Jean-Francois, Danede, Florence, Delcourt-Debruyne, Elisabeth, Descamps, Marc, Siepmann, Juergen

Journal:

Drug Development and Industrial Pharmacy

Year:

2015

Language:

english

File:

PDF, 2.98 MB

english, 2015

29

Characterization of ethylcellulose: starch-based film coatings for colon targeting

Karrout, Youness, Neut, Christel, Wils, Daniel, Siepmann, Florence, Deremaux, Laetitia, Desreumaux, Pierre, Siepmann, Juergen

Journal:

Drug Development and Industrial Pharmacy

Year:

2009

Language:

english

File:

PDF, 1.06 MB

english, 2009

30

Quaternary polymethacrylate–magnesium aluminum silicate films: Water uptake kinetics and film permeability

Rongthong, Thitiphorn, Sungthongjeen, Srisagul, Siepmann, Florence, Siepmann, Juergen, Pongjanyakul, Thaned

Journal:

International Journal of Pharmaceutics

Year:

2015

Language:

english

File:

PDF, 952 KB

english, 2015

31

Simulated food effects on drug release from ethylcellulose: PVA–PEG graft copolymer-coated pellets

Muschert, Susanne, Siepmann, Florence, Leclercq, Bruno, Carlin, Brian, Siepmann, Juergen

Journal:

Drug Development and Industrial Pharmacy

Year:

2010

Language:

english

File:

PDF, 502 KB

english, 2010

32

In vitro release studies of insulin from lipid implants in solution and in a hydrogel matrix mimicking the subcutis

Jensen, Sabrine S., Jensen, Henrik, Møller, Eva H., Cornett, Claus, Siepmann, Florence, Siepmann, Jürgen, Østergaard, Jesper

Journal:

European Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 2.92 MB

english, 2016

33

Chitosan-clay nanocomposite microparticles for controlled drug delivery: Effects of the MAS content and TPP crosslinking

Khlibsuwan, Rapee, Siepmann, Florence, Siepmann, Juergen, Pongjanyakul, Thaned

Journal:

Journal of Drug Delivery Science and Technology

Year:

2017

Language:

english

File:

PDF, 2.69 MB

english, 2017

34

When drugs plasticize film coatings: Unusual formulation effects observed with metoprolol and Eudragit RS

Karrout, Youness, Siepmann, Florence, Benzine, Youcef, Paccou, Laurent, Guinet, Yannick, Hedoux, Alain, Siepmann, Juergen

Journal:

International Journal of Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 1.03 MB

english, 2018

35

Implants pour la délivrance de principes actifs

Blanchemain, Nicolas, Siepmann, Florence, Siepmann, Juergen

Journal:

médecine/sciences

Year:

2017

Language:

french

File:

PDF, 3.08 MB

french, 2017

36

Towards a better understanding of the release mechanisms of caffeine from PLGA microparticles

Tamani, Fahima, Hamoudi, Mounira Chérifa, Danede, Florence, Willart, Jean‐François, Siepmann, Florence, Siepmann, Juergen

Journal:

Journal of Applied Polymer Science

Year:

2019

Language:

english

File:

PDF, 2.91 MB

english, 2019

37

Eudragit RL-based film coatings: How to minimize sticking and adjust drug release using MAS

Rongthong, Thitiphorn, Sungthongjeen, Srisagul, Siepmann, Florence, Siepmann, Juergen, Pongjanyakul, Thaned

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2020

File:

PDF, 4.56 MB

2020

38

Injection Molded Capsules for Colon Delivery Combining Time-Controlled and Enzyme-Triggered Approaches

Federica, Casati, Alice, Melocchi, Saliha, Moutaharrik, Marco, Uboldi, Anastasia, Foppoli, Alessandra, Maroni, Lucia, Zema, Christel, Neut, Florence, Siepmann, Juergen, Siepmann, Andrea, Gazzaniga

Journal:

International Journal of Molecular Sciences

Year:

2020

Language:

english

File:

PDF, 8.18 MB

english, 2020

39

Extracellular Vesicles and Biomaterial Design: New Therapies for Cardiac Repair

Pezzana, ChloÃ©, Agnely, Florence, Bochot, AmÃ©lie, Siepmann, Juergen, MenaschÃ©, Philippe

Journal:

Trends in Molecular Medicine

Year:

2020

File:

PDF, 531 KB

2020